What is the comparison of gelatin capsule shell and HPMC capsule shell?

Classification of hollow capsules As far as ordinary hollow capsule shells are concerned, the most common matrix materials are gelatin and hypromellose (HPMC). The comparison of gelatin capsule shells and HPMC capsule shells is as follows:

Gelatin Capsule Shell    HPMC Capsule Shell
Category: Animal Origin Capsule Shell
Main ingredient: Gelatin (from animal bone and skin)
+water
Production process: Gelatin is obtained from animal tissue through a series of processes such as degreasing and demineralization under appropriate conditions. Gelatin or HPMC is dissolved in water at an appropriate temperature to form a solution, a special mold is immersed in the hot solution, and the solution gels to form a film when cooled, and then undergoes post-processing such as drying and polishing.
Moisture content: 12.5~17.5%
Solubility: Swell in cold water at 25℃, insoluble
Crispy: none
Safety: safe and reliable, included in the multi-national pharmacopoeia

Category: Animal Origin Capsule Shell
Main ingredient: Hypromellose (from cotton linter, wood pulp)
+water
Moisture content: 4%~7%
Production process: Gelatin or HPMC is dissolved in water at an appropriate temperature to form a solution, a special mold is immersed in the hot solution, and the solution gels to form a film when cooled, and then undergoes post-processing such as drying and polishing.
Solubility: dissolve gradually in cold water at 25°C
Crunchy: Less than 5 out of 50
Safety: Excessive preservatives, mad cow disease risk

White Grey Gelatin capsule