What are the advantages of gelatin capsules?

Core Advantages of Gelatin Capsules

1. Superior Gastric Fluid Responsiveness
10-Minute Disintegration: Rapidly softens in the presence of gastric acid, accelerating drug release (plant-based capsules require over 20 minutes), critical for emergency medications (such as nitroglycerin) and analgesics.
No Brittleness at Low Temperatures: Remains tough even in a -25°C freezer, making it suitable for cold-chain biologics (such as insulin capsules).

2. Absolutely Competitive Production Costs
Inexpensive Raw Materials: Slaughterhouse byproducts (beef bones/pigskin) are highly utilized, costing only 30-50% of plant-based capsules (HPMC).
High-Speed ​​Mass Production: A single production line can produce 20 million capsules per day (plant-based capsule lines operate at half the efficiency), resulting in a short payback period.

3. Irreplaceable Barrier Protection
Oxygen Isolation: The dense structure of gelatin molecules offers a five-fold higher oxygen barrier than plant-based capsules, protecting easily oxidized drugs (such as vitamin E and fish oil).
Moisture-Resistant: In tropical high-humidity environments (humidity >70%), the water absorption rate of the contents is 40% lower than that of plant-based capsules. 

4. Strong Process Compatibility
High Filling: Suitable for encapsulating oily and pasty medications (such as hemorrhoid ointment capsules), as plant-based capsules are prone to leakage.
Print Adhesion: Micropores on the surface absorb ink, ensuring permanent labeling (plant-based capsules require laser etching, which increases costs).

5. Patient Compliance Advantages
Smooth Swallowing: Surface salivary proteins activate to form a water film, minimizing resistance in elderly and pediatric patients.
No Residual Odor: Maintains a neutral odor even after high-temperature sterilization (plant-based capsules have a cellulose odor that requires fragrance).