Drugs made into capsules are mainly based on the physical and chemical properties of the drug, and are considered from the following aspects:
First, some drugs have a stimulating effect on the esophagus and gastric mucosa. When taken apart, the local concentration is too high, which is easy to harm the esophagus and burn the throat, which is also highly irritating to the stomach. The second is that the taste of the medicine is not good, it is easy to be inhaled into the trachea and cause choking, or it is easy to be decomposed by saliva in the mouth. These medicines are put into capsules, which can cover up the bitterness and odor of the medicines, and eliminate the discomfort when taking the medicines. The third is that the medicine in the capsule has a prescribed dose, and it is easy to lose the powder after peeling, resulting in an inaccurate dose and affecting the effect of the medicine. Fourth, some capsules are enteric-coated capsules, and their function is to act as a protective shell to transport the drug all the way into the intestinal tract, so that the drug ingredients can avoid the decomposition of gastric acid and safely reach the intestinal tract before they can be effectively absorbed. Fifth, some capsules are slow-release capsules, which can prolong the release time of drug ingredients and make the drug effect more stable.
Therefore, the existence of the capsule shell not only protects the medicinal properties of the drug from being destroyed, but also protects the esophagus and respiratory tract; removing the capsule shell may cause the loss or waste of the active ingredients of the drug and reduce the efficacy of the drug.